In Germany, occupations are the structuring principle connecting the education system with the labour market and are thus considered important institutions for shaping employment histories. Yet empirical research has shown that male and female-dominated occupations come along with unequal employment opportunities. In this project, we therefore study the relevance of occupational sex segregation for the (re)production of gender inequalities in the German labour market. We approach the consequences of occupational sex segregation at an occupational and an individual level. In the first step, we analyse whether there is a relationship between occupational sex segregation and other occupational aspects, such as wage levels, proportion of part-time work, or qualification requirements. In the second step, we ask how these occupational features shape male and female employment histories and thereby contribute to the (re-)production of gender inequalities. Empirically, we first generate an occupational panel based on SIAB and Microcensus data to investigate long-term trends of occupational sex segregation and its causal relation with other occupational characteristics. These findings are then used to identify occupational characteristics that are relevant for generating gender inequality in employment histories. The respective occupational indicators are merged with NEPS Starting Cohort 6 data to examine their effects on different stages of female and male employment biographies, such as labour market entries, subsequent employment mobility, employment interruptions, and returns to work.